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It helps maintain a healthy nervous system and is also involved in the production of red blood cells

, Black M., Arballo J

Studies of Chinese Han population indicated that the T allele shown associated with schizophrenia as a risk allele 52 while a casecontrol association between the MTHFR C677T polymorphism and schizophrenia in a Japanese subjects research also demonstrated a strong linkage between the MTHFR C677T polymorphism and schizophrenia 53

Tabet F, Vickers KC, Cuesta Torres LF, Wiese CB, Shoucri BM, Lambert G, Catherinet C, Prado-Lourenco L, Levin MG, Thacker S, Sethupathy P, Barter PJ, Remaley AT, Rye KA

For example, an acute inflammatory response drives the transcription factor, NFB, to switch melatonin synthesis from pinealocytes to macrophages/microglia and, upon acute inflammatory resolution, back to pinealocytes

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