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It has been shown that individuals with psoriasis had a considerably higher serum S1P concentration [46], and that patients with SLE also have heightened S1P levels

This result is in line with LYMErixs historical evolution, which also depended on OspA as its primary antigen

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In the PNS, thiamine deficiency can result in polyneuritis and paralysis, as seen in dry beriberi, which affects the sensory system, causing pain, altered temperature sensitivity, numbness, reduced tendon reflexes, and leg atrophy (, , )

Reading the comments on this page has helped me to understand I am not alone with this reaction

Handling Notes Do not refreeze