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This could lead to the need to increase doses of some drugs to make them effective or could even result in resistance to the drugs

The impact of curcumin on arterial stiffness has also been investigated clinically and preclinically, with somewhat limited doseresponse data

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Besides the neutralization of free radicals produced in phase 1 liver metabolism of chemical toxins, GSH also participates in the protection from the resulting electrophilic substrates through the intervention of glutathione-S-transferases (GSTs)

Analysis of naphthoquinone derivatives as topoisomerase I inhibitors using fragment based QSAR

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