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Mota et al., 2021), cardiovascular disease (Wang et al., 2018), fatty liver disease (Hanai et al., 2020), male infertility (Barbagallo et al., 2020), kidney failure, and dialysis (Takashima et al., 2021)

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IDO catalyzes the conversion of TRP into kynurenine (KYN), which is converted into two metabolites: 3-hydroxykynurenine (3-HKYN) or kynurenic acid (KYNA)

10.1016/j.envpol.2019.02.087 114 HanJ.TaoW.CuiW.ChenJ

This happens because it helps your body use glucose more effectively [31]

Causes of cardiovascular disease and stroke: Visceral fat increases bad cholesterol (LDL), decrease good cholesterol (HDL), which leads to atherosclerosis, increased blood pressure and risk of myocardial infarction