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Second, as an endocrine-disrupting chemical, DEHP interferes with estrogen, androgen, progesterone, and thyroid hormone signaling

275 Another smaller phase 2 study enrolled 71 patients with MASH-related cirrhosis testing 2.4 mg semaglutide once weekly did not reveal significant changes in either the resolution of MASH or improvement in fibrosis despite some improvement of noninvasive markers of disease activity

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doi: 10.1136/gut.36.1.93