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M., Chen, J

The increased glucose (25 mM) was used to inhibit -cell glucagon secretion to diminish glucagon levels to basal levels to improve the dynamic range of the assay and thus effectively unmask the role of ligand-mediated glucagon secretion as described earlier 45

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This approach would simultaneously address the autoimmune attack (TA1) and promote repair of existing damage (TB4), potentially offering more comprehensive disease management than either peptide alone