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X.RanL.et al (2015)

[63] demonstrated that pharmacologically enhancing mitophagy (e.g., with urolithin A) can reduce mtDNA leakage and ameliorate inflammation in APP/PS1 mice

Taken together: Exercise exerts well-established neuroprotective and neurovascular benefits, including enhanced BDNF signaling and improved cerebral perfusion

Several pathways with a marked link to mitochondria were enriched in those patients

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