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In this review, we first describe the key molecular mechanisms of ferroptosis, and then discuss how these mechanisms operate and develop in AD

Several clinical studies have evaluated intranasal insulin in individuals with cognitive impairment or early AD, with some reporting improvements in memory performance and metabolic brain integrity (Hallschmid, 2021

pS09 and pS10 were constructed as follows

The RNA oligonucleotides used in this study, including Y-56 mimics, mimics-NC, Y-56 inhibitor, inhibitor-NC, si-IGF-1R, and si-NC, were obtained from Gene Pharma (Shanghai, China) and are shown in Table 1

Inhibition of the NRF2-ARE pathway abolishes the resistance to ART and GPX4 inhibitors, reversing the resistance of HNC cells to ferroptosis 56,57

N., Koyuncu, ., Kili, A., & Durgun, M