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Although RA patients have abnormally high levels of Treg cells in their synovial fluid (136140), these cells frequently have defective suppressive activity, and certain Foxp3+Treg cells may transform into pathogenic Th17 cells that secrete IL-17, thereby exacerbates inflammatory responses (141)
Froese D.S., Gravel R.A
In addition to the short length of the female urethra, which could easily allow the migration of bacteria from the anogenital area to the urethra and, therefore, to the bladder, other risk factors leading to the insurgence of UTIs are sexual activity as well as menopause [4,5]
doi: 10.23736/S0390-5616.20.05107-3
