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Description
Diminished levels of glutathione can lead to decreased efficiency in a number of body systems, including the immune cells designed to kill invading organisms

Ghisoni E, Imbimbo M, Zimmermann S, Valabrega G
2019;316:F743F757

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However, during reducing conditions, SOD1 efficiently binds to Rac1 and activates the NOX2 signaling pathway (Harraz et al., 2008)

Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease
