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Changes in its typically acidic pH leads to iron retention within the lysosome, resulting in impaired mitochondrial function 132

Reduction of SIRT1 activity compromises oxidative metabolism and antioxidant capacity, affecting complex I of the ETC, mitochondrial function and biogenesis (Rodgers et al., 2005)

ran HPLC in our lab and purity came back at 99.4%

[DOI] [PubMed] [Google Scholar] 9.Colberg SR, Sigal RJ