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Sativex also preserved myelin morphology in mice exposed to virus-induced demyelination

Increased catabolism leads to low plasma glutamine and is associated with low albumin levels, triggering severe inflammation and malnutrition

Therefore, this paradigm shift toward dynamic, ecology-informed oncology emphasizes three pillars: 1) Multiscale monitoring of tumor-host coevolution, 2) AI-driven prediction of adaptive resistance pathways, and 3) Therapeutic strategies that anticipate and redirect evolutionary selection pressures

Replacing the PEG-lipid component with zwitterionic polymers has improved LNP stability during nebulization, minimizing size increases and ensuring superior mucus penetration 192,193

Its clinical availability has depended on compounding pharmacy pathways, which have been subject to FDA review and revision