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Identification of nucleobase chemical modifications that reduce the hepatotoxicity of gapmer antisense oligonucleotides

Yet despite decades of research and advances in our knowledge of the etiologies of ASD, treatments and biomarkers for ASD remain limited [189]

The combination of these ingredients leads to a complex series of chemical and microbial reactions that drive the fermentation process [82] during which a new SCOBY layer forms on the surface of the liquid until it covers the solution completely [83]

10.1038/s41582-019-0244-7 76 IantornoM.CampiaU.Di DanieleN.NisticoS.ForleoG

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Although not approved for human consumption, KLOW marks an exciting time in the continued investment and development of peptide therapy as a future treatment