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Additionally, people with certain digestive disorders, such as Crohns disease or celiac disease, may struggle to absorb B12 from their diet and might require B12 injections to support digestive health

Bernardo-Castro et al

For many MetS patients, achieving recommended goals for healthy fat intake, blood pressure control, and blood glucose management may require a combination of medicine therapy, lifestyles, nutraceuticals, and others

doi: 10.3389/fphar.2025.1551062 Received 24 December 2024 Accepted 04 April 2025 Published 02 June 2025 Volume 16 - 2025 Edited by Yasmina Mohammed Abd-Elhakim, Zagazig University, Egypt Reviewed by Amany Abdel-Rahman Mohamed, Zagazig University, Egypt Ozlem Demirel, Baheehir University, Trkiye Updates Copyright 2025 Azzam, Anwar, Abd El-Slam, Diab, Ibrahim, Yousef, Sabry, Darwish, Kaliyamoorthy, Salem and Elsanhory

A histopathological investigation identified diseases such as inflammation, vacuolization, steatosis, and hepatocyte apoptosis, which were reversed by using silymarin (Vivekanandan et al., 2018)