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Specifically, 4-HNE has been shown to induce the nuclear localization of Nrf2, a transcription factor that regulates the expression of antioxidant proteins like heme oxygenase-1 (HO-1)
Supplementary material The Supplementary Material for this article can be found online at: References 1 AmiriA.CoppolaG.ScuderiS.WuF.RoychowdhuryT.LiuF.et al (2018)

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