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The use of broadspectrum antibiotics Penicillin and Amoxicillin can reduce the Bacteroides, Bifidobacterium, specifically Bifidobacterium adolescentis and Bifidobacterium bifidum , and Lachnospiraceae and Ruminococcaceae (Andrei et al

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Increased mitochondrial ROS formation has been associated with reduced mammalian target of rapamycin (mTOR)

If you take antibiotics, laxatives, or PPIs, youll end up with SIBO because all of those interrupt the gut bacteria

This, in turn, has been observed to trigger a series of events that result in the translocation of cytoplasmic P27KIP1 to the lysosome