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The integration of deep phenotypic profiling with multiomics data will be crucial for refining our mechanistic classifications and predicting treatment response

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Large-scale analysis uncovers somatic mutations changing berberine binding to 5 UTRs RNA-binding small molecules that target G4 structures in oncogenic 5 UTRs hold great promise for cancer therapy 28,29

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Certain mutations are more common in the United States, parts of Europe, and Asia

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