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While the exact reasons for that are unknown, it may be due to the three amino acid difference between human and rodent A or that mice do not live long enough (127)

G3 (Bethesda) 12, jkac013

Differential induction of renal heme oxygenase and ferritin in ascorbate and nonascorbate producing species transfused with modified cell-free hemoglobin

Beyond simply concentrating on B12 deficiency, it becomes paramount to address the matter of declined sensitivity to B12