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Additionally, it is found to induce inositol-1,4,5-trisphosphate (IP3)-mediated intracellular calcium signals in astrocytes, indicating key roles in neuroglial communication [47], and mediates astrocyte morphogenesis essential for downstream astrocytic support of neurons and synaptic function [48] as well as energy homeostasis and regulation of glutamate clearance [49]
Velez EJ, Unniappan S
Khaleghi et al
10.1124/jpet.107.131318
ISSN 0007-1447
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