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Spatial omics technologies, particularly the 10x Visium platform, have enabled simultaneous profiling of mitochondrial metabolic states and immune cell infiltration patterns at anatomical resolution, facilitating the initial construction of spatially resolved metabolismimmune interaction maps [168].In parallel, proteomics is increasingly recognized as a critical complement to transcriptomic and metabolomic data

MOTS-c preferentially reduces visceral adipose tissue in the research literature, which is why InBody-tracked patients at Perfect B often see visceral fat changes before overall weight changes

Taken together, this evidence suggests that gut microbiota plays a key role in BD