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While both medications influence these appetite pathways, the way they activate them is where the biggest difference appears

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Glucagonlike peptide (GLP-1) also stimulates the secretion of the hormone insulin, which in turn leads to the control of blood sugar levels in patients with type 2 diabetes

doi: 10.1111/j.1742-481X.2012.01022.x [DOI] [PMC free article] [PubMed] [Google Scholar] 182

An analysis using five years of medical records from tens of thousands of adults diagnosed with obesity and Type 2 diabetes showed "statistically significant increases" of the conditions, the American Academy of Orthopedic Surgeons said in a statement