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Front Immunol (2018) 9:1127
doi: 10.1016/j.canlet.2020.01.019 46 ChecaJAranJM

Furthermore, many antioxidant nutrients (e.g., vitamins, polyphenols) might protect circadian homeostasis by counteracting oxidative stress, which is known to impair clock function

Gombart AF, Pierre A, Maggini S (2020) A review of micronutrients and the immune system-working in harmony to reduce the risk of infection

Excess iron deposits in vital organs such as the liver, heart, and endocrine glands, leading to progressive complications including cardiac failure, liver fibrosis, and endocrine dysfunction
