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Some studies indicate that the risk is also due to higher homocysteine levels[ref], while other studies show that it may be due to the methylation of certain genes.[ref] Meta-analyses showed that the MTHFR C677T variant increased the risk of migraines with aura for all population ancestry groups

H., Public Awareness and Stigma of Autism Spectrum Disorder in Iran

Another cross-sectional study using an electronic medical record database found that lower serum UA levels increased the incidence of PD, sped up the disease course, and aggravated motor problems and cognitive impairment with long-term dopaminergic medication (Dnu et al., 2022)

Tudhope GR, Swan HT, Spray GH

doi: 10.2337/diabetes.55.02.06.db05-0885 100 MalikRAWilliamsonSAbbottCCarringtonALIqbalJSChadyWet al

Discuss these potential mild effects so patients know they are normal