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For DMSO concentrations of 0.5% and 1%, larval metabolism was not significantly affected when comparing mean fluorescence intensities of treated against untreated larvae using the Dunnetts multiple-comparisons test

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APR-246 potently inhibits tumour growth and overcomes chemoresistance in preclinical models of oesophageal adenocarcinoma

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Comparative studies on therapies for IBD also reflect these results, confirming the importance of TNF- inhibitors for the treatment of inflammatory diseases