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Given the rich lipid content of the nervous system, hemoglobin-derived iron works with lipid peroxidation to induce ferroptosis, which eventually leads to neuronal mitochondrial damage, edema, and apoptosis of neurons and astrocytes

These studies allow us to refine the formulation iteratively, ensuring that the liposomes meet functional requirements before scale-up

[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Roussel M, Saule S, Lagrou C, et al

Reduced-frequency maintenance and full discontinuation produce different outcomes

In the tibolone group, fibroid size increased by 4.7% during the same time period (Xi 2014)

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