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Beyond immediate glycemic control, GLP-1 signaling enhances -cell function, promotes -cell proliferation, and inhibits apoptosis in preclinical models [53]

The risk factors for developing anthracycline-induced cardiotoxicity are cumulative anthracycline dose, advanced age, pretreatment low-normal LVEF, prior cardiovascular disease, as well as other established cardiovascular risk factors (e.g., hypertension, diabetes, obesity, smoking)

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