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The antioxidant activity of flavonoids depends on the availability of the donation of phenolic hydrogens (Rice-Evans et al

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In response, Empower told the FDA that it was improving its manufacturing processes, but in 2018, the FDA investigators again noted in an inspection report that Empower was not adequately investigating problems with sterile drug quality

Furthermore, the presence of carbonyl groups, such as aromatic acids, esters, or lactones, enhances antioxidant activity, especially when the carbonyl group is separated from the aromatic ring

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