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Population-based cancer incidence and mortality rates and ratios among adults with intellectual disabilities in Scotland: a retrospective cohort study with record linkage

FIGURE 4 4 Discussion Air pollution has been considered as a worldwide public health concern and has drawn more attention recently ( The PM2.5 concentration in Shijiazhuang is extremely high, with annual average PM2.5 concentrations as high as 138.8 g/m 3 in 20142016 ( 3 and SO 4 2 ) in the water-soluble fraction ( According to a World Health Organization survey in 2020, 38.9 million children under the age of five were overweight worldwide, and the number of adolescents and adults population suffering from obesity reached 340 million and 650 million, respectively ( It is well known that the development of overweight and obesity is accompanied by excessive storage of lipids in adipose tissue ( The crosstalk between the liver and adipose tissue is pivotal for regulating lipid metabolism

Mast cell-derived mediators, including leukotrienes (LTs), histamine, and interleukins, contribute to bronchoconstriction, airway inflammation, and structural remodeling across different asthma endotypes