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Sham-operated rats were subjected to the same surgical procedure except for the MCA occlusion

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Serotonin, a critical neurotransmitter that plays a major role in regulating mood, is frequently observed at lower levels in people suffering from depression

Cancer Cell 16(6):510520

Curcumin It is a polyphenolic compound obtained from turmeric rhizomes [93].Its wide usage arises from its minimal side effects alongside its plentiful therapeutic benefits such as antioxidant, anti-inflammatory, anticancer, antimicrobial and antidiabetic effects [94,95,96,97]Curcumin has been shown to have eminent neuroprotective properties in a variety of neurodegenerative diseases, including Alzheimer disease and Parkinson disease [98]

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