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AOD-9604 has human clinical trial data and FDA GRAS status

TNF- signalling and inflammation: interactions between old acquaintances

2020;574 doi: 10.1016/j.ijpharm.2019.118849

Banerjee P., Kemmler E., Dunkel M., and Preissner R., ProTox 3.0: A Webserver for the Prediction of Toxicity of Chemicals, Nucleic Acids Research 52 (2024): W513W520, 10.1093/nar/gkae303

The amount of cyanide in cyanocobalamin is so minuscule it's not a problem for the body if you have healthy kidney function, but if you're a smoker (cigarette smoke contains high amounts of cyanide) or consume large amounts of cassava (naturally high in cyanide) then cyanocobalamin isn't recommended as your tissues may contain too much cyanide for cyanocobalamin to be converted

The other authors report no conflicts of interest