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Elevated ROS levels are associated with enhanced lipid metabolism, high lipid peroxidation, modification of cellular oxidation states, DNA breakage, changes in gene expression, or even cell death (17, 2729)

(2020) 180:10811097.e24

[DOI] [PMC free article] [PubMed] [Google Scholar] 41.Maurya V.K., Shakya A., McClements D.J., Srinivasan R., Bashir K., Ramesh T., Lee J., Sathiyamoorthi E

Targeting MAPK14 by lobeline upregulates slurp1-mediated inhibition of alternative activation of TAM and retards colorectal cancer growth

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The brain concentrations and B/P ratios of risperidone (13.1-fold and 12-fold) and 9-hydroxyrisperidone (29.4-fold and 29-fold) were significantly higher in the ABCB1 knockout mice than wild-type mice