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Several studies have shown that SDH-deficient cells exhibit increased tumorigenesis and that this increase is reversed by the addition of -KG, supporting the idea that succinate accumulation contributes to tumorigenesis through epigenetic modification 100
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Prevention of L-dopa-induced growth hormone stimulation by hyperglycemia
doi: 10.1186/s13075-023-03181-w [DOI] [PMC free article] [PubMed] [Google Scholar] 256.Lucas V, Cavadas C, Aveleira CA
gabbr1-forward (loss): CAG TCG ACA AGC TTA GTG GAT CC
Cruciferous vegetables like broccoli, Brussels sprouts, cabbage, and kale are excellent sources, as are allium vegetables including garlic and onions
