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For example, compounds like quercetin (found in apples and onions) and resveratrol (found in grapes) have been shown to inhibit the activation of NF-B, a master genetic switch that controls the expression of numerous inflammatory genes
There is substantial evidence that the expression of SOCS3 protein increases with aging in several cells/tissues, such as rat myocardium [162], hypothalamus [163], and human blood mononuclear cells [164] as well as human sarcopenic skeletal muscles [165] and the brains of Alzheimers patients [166]

Meta-analysis of Parkinsons disease and Alzheimers disease revealed commonly impaired pathways and dysregulation of NRF2-dependent genes

doi: 10.1042/bj2390121

[PubMed] [Google Scholar] 109.Wass JAH, SS, Gale E, Amiel SA

This is truly why SIBO symptoms rarely stay limited to the gut
