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Histone Kla can cause an increase in M2 phenotype-related proteins, indicating that it promotes the transformation of TAMs from the proinflammatory, anticancer M1 phenotype to the antiinflammatory, procancer M2 phenotype

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Key Functional Differences: NAD+: For energy production and DNA repair Glutathione: For antioxidant defense (fighting free radicals and regenerating other antioxidants) and detoxification NAD vs Glutathione: How They Work Should You Choose NAD or Glutathione

TNF- can be considered an alarm signal that activates immune cells and other molecules during liver stress

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