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Lipoic acid has been shown to inhibit the JNK pathway and IRS1 serine phosphorylation, resulting in improved insulin sensitivity

[DOI] [PubMed] [Google Scholar] Guan Y., Zheng X.M., Yang Z.W., Li S.W

Sub-synovial fat was free of inflammation, fibrosis, or vascular proliferation

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Global epidemiology of diabetic foot ulceration: a systematic review and meta-analysis
