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Braz J Med Biol Res 51:e7172 Wang X-J, Sun Z, Villeneuve NF, Zhang S, Zhao F, Li Y, Chen W, Yi X, Zheng W, Wondrak GT (2008) Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

Due to the non-apoptotic nature of ferroptosis, ferroptosis-based cancer treatments are expected to bypass the shortcomings of traditional therapies mediated by apoptotic pathways [225]

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