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Testing: Third-party lab report available where provided

Studies in vitro have shown that exposure to calcitriol or certain vitamin D analogues can slow sebocyte proliferation, arrest their growth cycle, and reduce lipid production in a dose-dependent manner, suggesting a potential seboregulating effect

The metal chelating activity of flavonoids results either (i) in the formation of metal-chelates which have lower catalytic efficiency in Fenton reaction than pure flavonoids (decreased number of metal binding sites is usually associated with lower catalytic activity) or (ii) metal flavonoid chelates can intercalate into DNA of cancer cells, triggering cell death (Simunkova et al

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