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PMID: 28809450

In MASLD, elevated leptin levels contribute to the development of IR, a hallmark feature of the disease

Finally, there is evidence that normal ranges of Se change depending on age and gender (e)

Adiponectin: Adiponectin is a protective adipokine primarily secreted by adipose tissue that enhances insulin sensitivity, reduces oxidative stress, and exerts anti-inflammatory effects

Doses used were well tolerated by patients, while only mild adverse effects were reported (heartburn, nausea, flatulence) [60]

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