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The determination of the GSH level is based on Ellmans method [55], in which 5,5-dithiobis-(2-nitrobenzoic acid) (DTNB, Sigma-Aldrich, Darmstadt, Germany) is reduced by -SH groups present in the sample, resulting in a product with an intense yellow color

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The patients who succeed through month 2 are the ones who throw everything at the problem, not the ones who try to minimize or endure without help

HIF-1 is a prominent pathway recently implicated in ROS homeostasis

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[DOI] [PubMed] [Google Scholar] 55.Rustenhoven-Spaan I, Melkert P, Nelissen E, van Roosmalen J