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**Key Findings:** * The redesigned Grx1roGFP2 sensor exhibited improved fluorescence intensity, targetability, and maintained redox sensitivity

Inhibition of GPX4 induced rapid and selective lipid ROS accumulation and cell death across a panel of human and murine DLBCL cellular models irrespective of subtype

Inflammation: Some studies suggest Ashwagandha may possess anti-inflammatory properties, but more research is needed to understand its potential applications

Important Health Reminder: Supplements work differently for everyone and are not a substitute for medical care