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PERIPHERAL ADIPOSITY SIGNALS Leptin The obese gene coding leptin was first identified by positional gene cloning of ob/ob mice in 1994 [21]

IGF1 indirectly increases DNA repair by 50% through increasing the p53 dependence in the p21, while inhibition IGF1R by siRNA in human prostate cancer cells enhances the sensitivity of ionizing radiation to SSBs and DSBs (Clark et al., 2005)

What Are the Benefits of Glutathione IV Therapy