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10.1016/J.ECOENV.2023.114912 114 WangC.LiZ.HanH.LuoG.ZhouB.WangS.et al (2016a)

Methylglyoxal is a reactive dicarbonyl molecule that can be generated from metabolites originating in glycolysis (dihydroacetone phosphate), lipolysis (acetol), and amino acid degradation (aminoacetone)

Reungwetwattana T, Eadens MJ, Molina JR

Selenium supplementation could increase GPX4 expression in T cells, thereby leading to an increase in Tfh cell numbers and improved antibody responses in vaccinated mice and young adults post-influenza vaccination (97)

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While the CNS is generally considered protected from peripheral aAB by an intact BBB, it may be vulnerable to autoimmune attack during states of peripheral inflammation or endothelial dysfunction that disrupt the BBB and thus allow for increased antigen presentation and immigration of immune cells (Lampron et al., 2013