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Yap S, Naughten ER, Wilcken B, Wilcken DE, and Boers GH (2000)

163 Wnt/-catenin pathway in AD AD is mainly characterized by neuronal loss, the deposition of amyloid-beta plaques, and the formation of hyperphosphorylated tau protein in neurons, particularly the cytotoxic effect of amyloid beta-peptide (Abeta)

PMID: 10458244

doi: 10.1161/CIRCULATIONAHA.122.060785 151 NunesJMKrugerAProalAKellDBPretoriusE

In patients with MCAS, mobilizing toxins too quickly can trigger severe mast cell degranulation, leading to hives, flushing, gastrointestinal distress, and even anaphylaxis-like reactions