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In addition, it has been demonstrated that these anti-CD38 mAbs also have a potential in vivo immune modulatory effects on the tumor microenvironment such as enhancing effector T-cell function and inhibiting suppressive T-reg activity (42)

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Int J Obes (Lond) 2006;30(12 ): 172936

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Innovations in GLP-1 Agonist Therapies The success of GLP-1 agonists in both diabetes management and weight loss has spurred further innovation in this drug class, leading to the development of new generations with improved efficacy, safety, and patient convenience

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