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[DOI] [PMC free article] [PubMed] [Google Scholar] 21.Steinmetz-Sph J., Liu J., Singh R., et al
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Anti-NGF monoclonal antibodies have demonstrated analgesic activity in osteoarthritis but are associated with joint-specific safety signals, including increased rates of rapidly progressive osteoarthritis in phase III trials (7274)
The SPOC domain of PHF3 was recently identified as a CTD reader domain specifically binding to phosphorylated serine-2 residues in adjacent CTD repeats
That is, the coformulation comprising 6 mM histidine was the most physically stable
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