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While MLKL KO mice were protected from steatohepatitis in various models, symptoms could be exacerbated in RIPK3-/- mice
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The breakdown products are then transported out of the cell and further metabolized, either through acetylation to form mercapturic acids, catalyzed by N-acetyltransferases, or through carbonsulfur bond breakage mediated by cysteine-S-conjugate -lyase
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