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The TSH level was measured before and after treatment with 1 g/day of vitamin C administered with levothyroxine, while the levothyroxine dose was constant, and it was found that the patients had statistically lower TSH levels after the intervention

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The radioisotope probe assay is a cost-effective and fast method for generating informative data for early preclinical/pharmacokinetic absorption, digestion, metabolism, and excretion studies of biotherapeutics (Roffey et al., 2007