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Because DSIP may interact with neurotransmitter systems such as GABA and NMDA pathways, combining it with sedatives, alcohol, or other neuroactive substances could amplify drowsiness or increase the risk of neurological side effects

[DOI] [PubMed] [Google Scholar] [161].Spiegelman BM, Transcriptional control of mitochondrial energy metabolism through the PGC1 coactivators

Unfortunately, the most common form of B12 in supplements and fortified foods is Cyanocobalamin which is not as effective as Methylcobalamin

Because there are so many different causes and types of muscle cramps, many different medical specialists may be involved in their treatment

Vitamin B 12 deficiency can result in subacute combined degeneration of the spinal cord (SACD), and several case reports have pointed to patients with both DCM and SACD