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Individuals with hypersomnia related to a psychiatric disorder (n = 23) had more sleep disturbance signs on nocturnal PSG (higher sleep latency, wakefulness after sleep onset, total wake time) and longer sleep latency during daytime naps than individuals with primary hypersomnia (based on DSM-IV criteria, superseded by hypersomnolence disorder in DSM-5-TR

Moreover, peroxisome proliferator-activated receptor-, a nuclear receptor essential for fatty acid oxidation, is often downregulated, impairing lipid breakdown

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Cell 187, 16511665.e21

Targeted supplements can help fill the gaps and support memory, focus and mental energy