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Description
The dosage of B12 required depends on three key factors

10.1007/s00134-019-05703-0 2

If you do, in fact, have a B12 deficiency, injections of the vitamin will reduce the following symptoms and restore your energy as well as your metabolism
Serum B12 and a full blood count should be checked when macrocytosis or anaemia is identified alongside an unexpected HbA1c result

Many payers also require step therapy documentation (proof the patient tried lower-cost alternatives)

So, what constitutes a compromised immune system
